|The UBE2V2 ube2v2 (Catalog #MBS1491520) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Ubiquitin-conjugating enzyme E2 variant 2 polyclonal Antibody, FITC reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Ubiquitin-conjugating enzyme E2 variant 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA). Researchers should empirically determine the suitability of the UBE2V2 ube2v2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The UBE2V2 ube2v2 product has the following accession number(s) (GI #4507797) (NCBI Accession #NP_003341.1) (Uniprot Accession #Q15819). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through \'Lys-63\'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Storage Buffer: Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate: FITC. Immunogen: Recombinant human Ubiquitin-conjugating enzyme E2 variant 2 protein
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-292685. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing UBE2V2 are readily searchable from our website. Different antibodies against the same target such as UBE2V2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Brain, Embryonic Tissue, Heart, Intestine, Lung, Stomach tissues are correlated with this protein. UBE2V2 also interacts with the following gene(s): OTUB1, PCNA, RNF8, SHPRH, UBC, UBE2N, UBE2V1. The following patways have been known to be associated with this gene.