anti-UCP3 antibody product blog
Tags: Antibody; UCP3; Polyclonal Antibody; anti-UCP3 antibody;
The UCP3 ucp3 (Catalog #MBS2518876) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The UCP3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s UCP3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). Researchers should empirically determine the suitability of the UCP3 ucp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The UCP3 ucp3 product has the following accession number(s) (GI #2183021) (NCBI Accession #AAC51367.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the UCP3 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of various cell lines, using UCP3 antibody.)
Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver cancer using UCP3 antibody at dilution of 1:200 (x400 lens))
Immunofluorescence (IF) (Immunofluorescence analysis of MCF7 cell using UCP3 antibody. Blue: DAPI for nuclear staining.)
The uncoupling protein UCP1 (formerly designated UCP) is an integral membrane protein unique to brown adipose tissue mitochondria. UCP1 forms a dimer that acts as a proton channel, which can uncouple oxidative phosphorylation by dissipating the electrochemical potential across the inner mitochondrial membrane. This process induces heat production in brown adipose tissue and is involved in regulation of body temperature and glucose metabolism. UCP2 is a structurally related protein that also uncouples mitochondrial respiration. It is more widely expressed in human and mouse tissues, including white adipose tissue and muscle, than is UCP1. UCP2 is thought to play a role in body weight regulation. An additional UCP family member, UCP3, is highly muscle specific and is possibly involved in the uncoupling of oxidative phosphorylation in skeletal muscle.
Immunogen: Recombinant protein of human UCP3
Observed Molecular Weight: 34kDa. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-7756 / sc-31385 / sc-31387. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing UCP3 are readily searchable from our website. Different antibodies against the same target such as UCP3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.