anti-VANGL2 antibody product blog
Tags: Antibody; Polyclonal Antibody; VANGL2; anti-VANGL2 antibody;
The VANGL2 vangl2 (Catalog #MBS9207640) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VANGL2 Antibody (C-Term) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s VANGL2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).WB~~1:2000. Researchers should empirically determine the suitability of the VANGL2 vangl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The VANGL2 vangl2 product has the following accession number(s) (GI #62955805) (NCBI Accession #NP_065068.1) (Uniprot Accession #Q9ULK5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the VANGL2 Antibody (C-Term) with the following immunoassay(s):
Western Blot (WB) (Anti-VANGL2 Antibody (C-Term)at 1:2000 dilution + DU145 whole cell lysates
Lysates/proteins at 20 ug per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution
Predicted band size : 60 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.)
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity).
Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing VANGL2 are readily searchable from our website. Different antibodies against the same target such as VANGL2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Breast Neoplasms, Edema, Heart Defects, Congenital, Intestinal Neoplasms, Kidney Diseases, Lung Neoplasms, Nervous System Diseases, Neural Tube Defects, Spinal Dysraphism are some of the diseases may be linked to VANGL2 Antibody (C-Term). VANGL2 also interacts with the following gene(s): CELSR1, DVL1, DVL2, DVL3, FZD3, PRICKLE1, PRICKLE2, ROR2, RYK, WNT5A. Brain, Connective Tissue, Embryonic Tissue, Eye, Lung, Muscle, Prostate, Skin, Trachea, Uterus tissues are correlated with this protein.