|The VASP vasp (Catalog #MBS6013068) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VASP, CT (VASP, Vasodilator-stimulated phosphoprotein) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s VASP can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50. Researchers should empirically determine the suitability of the VASP vasp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The VASP vasp product has the following accession number(s) (GI #4507869) (NCBI Accession #NP_003361.1) (Uniprot Accession #P50552). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.
Immunogen: VASP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-296 amino acids from the C-terminal region of human VASP. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing VASP are readily searchable from our website. Different antibodies against the same target such as VASP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Embryonic Tissue, Kidney, Liver, Lung, Muscle, Stomach, Vascular tissues are correlated with this protein. VASP also interacts with the following gene(s): CXCR2, FYB, LPP, PFN1, PFN2, PRKG1, RAPH1, ZYX. The following patways have been known to be associated with this gene. Atherosclerosis, Breast Neoplasms, Disease Models, Animal, Hypertension, Hypertrophy, Inflammation, Neoplasms, Nervous System Diseases, Pain, Thrombosis are some of the diseases may be linked to VASP, CT (VASP, Vasodilator-stimulated phosphoprotein).