anti-VEGF R2 antibody product blog
Tags: Antibody; Polyclonal Antibody; VEGF R2; anti-VEGF R2 antibody;
The VEGF R2 n/a (Catalog #MBS618634) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The VEGF R2 (FLK1/KDR) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s VEGF R2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry.
Dilution: Immunofluorescence: 1:50-1:100
Western Blot: 1:500-1:2000
Immunohistochemistry: 1:50-1:100 (ABC). Researchers should empirically determine the suitability of the VEGF R2 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the VEGF R2 (FLK1/KDR) with the following immunoassay(s):
Testing Data (Staining in FFPE human angiosarcoma using MBS618634.)
VEGF receptor 2 is a member of a receptor tyrosine kinase family whose activation plays an essential role in a large number of biological processes such as embryonic development, wound healing, cell proliferation, migration and differentiation. Like other growth factor receptors, upon ligand binding VEGF receptor 2 dimerises and is autophosphorylated on multiple tyrosine residues. These sites can be involved in the regulation of kinase activity or serve as binding sites for SH2 and phosphotyrosine binding containing signalling proteins. Phosphorylation of Tyrosines 1054 and 1059 in the activation loop is required for activation of VEGF receptor 2 and its intrinsic tyrosine kinase activity.
Immunogen: Synthetic peptide derived from the C-terminus of the precursor form of the mouse VEGF R2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing VEGF R2 are readily searchable from our website. Different antibodies against the same target such as VEGF R2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.