anti-VEGFR-3/FLT-4 antibody product blog
Tags: Antibody; Polyclonal Antibody; VEGFR-3/FLT-4; anti-VEGFR-3/FLT-4 antibody;
The VEGFR-3/FLT-4 flt4 (Catalog #MBS691442) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Anti-Human VEGFR-3/FLT-4 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s VEGFR-3/FLT-4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA), Immunohistochemistry (IHC).Western Blot: Use at 1-2 ug/ml ELISA: Use at 1-5 ug/ml Others For IP use 1-5 ug/ml IF/IHC Cryo sections. Researchers should empirically determine the suitability of the VEGFR-3/FLT-4 flt4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The VEGFR-3/FLT-4 flt4 product has the following accession number(s) (GI #103472027) (NCBI Accession #NP_002011) (Uniprot Accession #P35916). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Anti-Human VEGFR-3/FLT-4 with the following immunoassay(s):
Testing Data
Receptor tyrosine Kinase VEGFR-3, also known as FLT4, together with VEGFR1 (FIT1) and VEGFR2 (KDR/Flk-1), are the receptors for vascular endothelial growth factors (VEGF). The VEGFR family belongs to the class II subfamily of receptor tyrosine kinases (RTKs), containing a large extracellular region which is composed of seven Ig-like domains (D1 -D7), a single transmembrane (TM) helix and cytoplasmic region with a tyrosine kinase activity. In VEGFR-3, the fifth Ig homology domain is proteolytically cleaved which results in polypeptides remain linked by two disulfide bonds. VEGFR-3 is widely expressed on all endothelia cells in early embryogenesis, while, in adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGF-C and VEGF-D activation of VEGFR-3 plays an important role in the formation of the lymphatic vessel system.
Immunogen: Recombinant human sFLT-4 (D1-7)
Preparation: Produced from sera of rabbits immunised with highly pure recombinant human soluble VEGFR-3/FLT-4 (D1-7). Buffer: PBS. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing VEGFR-3/FLT-4 are readily searchable from our website. Different antibodies against the same target such as VEGFR-3/FLT-4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.