anti-WAPAL antibody product blog
Tags: Antibody; Polyclonal Antibody; WAPL; anti-WAPAL antibody; WAPAL;
The WAPAL wapal (Catalog #MBS153367) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WAPL Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s WAPL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).WAPL antibody can be used for detection of WAPL by Western blot at 1 - 2 mug/ml. Antibody can also be used for Immunohistochemistry at 5 mug/mL. For Immunoflorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the WAPAL wapal for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The WAPAL wapal product has the following accession number(s) (GI #42734325) (NCBI Accession #NP_055860) (Uniprot Accession #Q7Z5K2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the WAPL Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of WAPL in A20 cell lysate with WAPL antibody at (A) 1 and (B) 2 μg/ml.)
Immunohistochemistry (IHC) (Immunohistochemistry of WAPL in rat heart tissue with WAPL antibody at 5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of WAPL in rat heart tissue with WAPL antibody at 20 μg/mL.)
WAPL (wings apart-like), also known as WAPAL or FOE, is a 1,190 amino acid protein that contains one WAPL domain and may play an important role in cell growth (1). It is expressed in an isoform dependent manner in heart, skeletal muscle (isoform 2) and uterine cervix tumor tissue (isoform 1) (1,2,4). WAPL is involved in sister-chromatid adhesion and promotes release of cohesin from chromosomes by directly interacting with its regulatory subunits (3,4). WAPL is a new regulator of the development and metastasis of cancerous tissue (4,5).
Conjugate: Unconjugated
Immunogen: WAPL antibody was raised against an 18 amino acid peptide near the amino terminus of human WAPL.
Buffer: WAPL antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing WAPAL are readily searchable from our website. Different antibodies against the same target such as WAPAL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.