anti-WISP2 antibody product blog
Tags: Antibody; WISP2; Polyclonal Antibody; anti-WISP2 antibody;
The WISP2 wisp2 (Catalog #MBS625450) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WISP2, ID (WNT1-inducible-signaling Pathway Protein 2, WISP-2, Connective Tissue Growth Factor-like Protein, CTGF-L, Connective Tissue Growth Factor-related Protein 58, CCN Family Member 5, CCN5, CT58, CTGFL, UNQ228/PRO261) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s WISP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:1,000
Western Blot: 1:100-1:500. Researchers should empirically determine the suitability of the WISP2 wisp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The WISP2 wisp2 product has the following accession number(s) (GI #4507923) (NCBI Accession #NP_003872.1) (Uniprot Accession #O76076). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the WISP2, ID (WNT1-inducible-signaling Pathway Protein 2, WISP-2, Connective Tissue Growth Factor-like Protein, CTGF-L, Connective Tissue Growth Factor-related Protein 58, CCN Family Member 5, CCN5, CT58, CTGFL, UNQ228/PRO261) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of anti-WISP2 Antibody (Center) in A549 cell lysate. Wisp2 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.)
Immunohistochemistry (IHC) (WISP2 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of WISP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Wisp2 a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain. Wisp2 lacks the CT domain which is implicated in dimerization and heparin binding. It is 72% identical to the mouse protein at the amino acid level. This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors. It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.