anti-WWOX2 antibody product blog
Tags: Antibody; Polyclonal Antibody; WWOX2; anti-WWOX2 antibody;
The WWOX2 wwox (Catalog #MBS5400255) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The WWOX2 Antibody FITC-Conjugated reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s WWOX2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).Dot Blot: 1:10,000-1:100,000
ELISA: 1:10,000-1:100,000
Western Blot: 1:500. Researchers should empirically determine the suitability of the WWOX2 wwox for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The WWOX2 wwox product has the following accession number(s) (GI #15667688) (NCBI Accession #AAL05451.1) (Uniprot Accession #Q9NZC7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
FITC-Conjugated Abberant WW domain-containing Oxidoreductase Antibody
Putative oxidoreductase. Acts as a tumor suppressor and plays a role in apoptosis. Required for normal bone development (By similarity). May function synergistically with p53/TP53 to control genotoxic stress-induced cell death. Plays a role in TGFB1 signaling and TGFB1-mediated cell death. May also play a role in tumor necrosis factor (TNF)-mediated cell death. Inhibits Wnt signaling, probably by sequestering DVL2 in the cytoplasm.
Immunogen: Synthetic peptide corresponding to unique amino acid sequence on WWOX2 protein.
Expression: Widely expressed. Strongly expressed in testis, prostate, and ovary. Overexpressed in cancer cell lines. Isoform 5 and isoform 6 may only be expressed in tumor cell lines. Molecular Function: Coenzyme binding; protein dimerization activity; cofactor binding;
Structure: Interacts with TP53, p73/TP73 and MAPK8. Interacts with MAPT/TAU, RUNX2 and HYAL2 (By similarity). Forms a ternary complex with TP53 and MDM2. Interacts with ERBB4, LITAF and WBP1. Interacts with DVL1, DVL2 and DVL3. May interact with FAM189B and SCOTIN.
Subcellular Location: Cytoplasm. Nucleus. Mitochondrion. Golgi apparatus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing WWOX2 are readily searchable from our website. Different antibodies against the same target such as WWOX2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Breast Neoplasms, Carcinoma, Cell Transformation, Neoplastic, Chromosome Aberrations, Liver Neoplasms, Lung Neoplasms, Neoplasm Metastasis, Neoplasms, Experimental, Nervous System Diseases, Ovarian Neoplasms are some of the diseases may be linked to WWOX2 Antibody FITC-Conjugated. WWOX2 also interacts with the following gene(s): ERBB2, ERBB4, EZR, MAPK8, SRC, TNK2, TP53, YAP1.