|The XIAP xiap (Catalog #MBS280118) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Human X-Linked Inhibitor Of Apoptosis Protein (XIAP) polyclonal antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s X-Linked Inhibitor Of Apoptosis Protein can be used in a range of immunoassay formats including, but not limited to, Western Blot Analysis (WB), Immunohistochemistry (IHC), ELISA (EIA). Researchers should empirically determine the suitability of the XIAP xiap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The XIAP xiap product has the following accession number(s) (GI #1184320) (NCBI Accession #AAC50373.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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X-linked Inhibitor of Apoptosis Protein (XIAP) is a member of the Inhibitor of apoptosis family of proteins (IAP). IAPs were initially identified in baculoviruses, but XIAP is one of the homologous proteins found in mammals. It is so called because it was first discovered by a 273 base pair site on the X chromosome.The protein is also called human IAP-like Protein (hILP), because it is not as well conserved as the human IAPS: hIAP-1 and hIAP-2. XIAP is the most potent human IAP protein currently identified.XIAP, like the rest of the IAP family, has two major structural elements. Firstly, there is the baculoviral IAP repeat (BIR) domain consisting of approximately 70 amino acids. Secondly, there is a zinc-binding domain, or a "carboxy-terminal RING Finger".
Storage Buffer: PBS, pH: 7.20, 1% BSA, 0.02% Sodium azide.
Immunogen: Recombinant protein, corresponding to the N-term of human XIAP. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing XIAP are readily searchable from our website. Different antibodies against the same target such as XIAP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.