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anti-XIAP antibody product blog

Posted on 2015-07-21 22:56:39 by mybiosource_staff
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Tags: Antibody; XIAP; Polyclonal Antibody; anti-XIAP antibody;
The XIAP n/a (Catalog #MBS621779) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XIAP (X Linked Inhibitor of Apoptosis, X-linked Inhibitor of Apoptosis Protein, X-linked IAP, Apoptosis Inhibitor 3, API3, Baculoviral IAP Repeat Containing 4, Baculoviral IAP Repeat-containing Protein 4, BIRC4, HILP, IAP 3, IAP3, IAP-like Protein, ILP-1, reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s XIAP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the XIAP n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The XIAP n/a product has the following accession number(s) (GI #150036276). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

The human X chromosome linked Inhibitor of Apoptosis Protein (XIAP) is a major member of the inhibitor of apoptosis (IAP) family. XIAP functions by direct binding and inhibition of several caspases, including Caspase 3, Caspase 7 and Caspase 9. During apoptosis XIAP is specifically cleaved by Caspase 3 and partially loses its function. In addition to blocking the apoptosis signaling pathway, XIAP can also bind several other proteins in the bone morphogenetic protein (BMP) signaling pathway and act as a coupler between the membrane BMP receptor and the TAB1 TAK1 complex by binding to these proteins.

XIAP n/a

In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing XIAP are readily searchable from our website. Different antibodies against the same target such as XIAP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. XIAP also interacts with the following gene(s): FLNA. Bone, Brain, Connective Tissue, Ear, Embryonic Tissue, Heart, Kidney, Muscle, Umbilical Cord, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.
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