|The XRCC3 xrcc3 (Catalog #MBS9406767) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The XRCC3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s XRCC3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
Western blotting: 1:500 - 1:2000
Immunohistochemistry: 1:50 - 1:100
Immunofluorescence: 1:50 - 1:200. Researchers should empirically determine the suitability of the XRCC3 xrcc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The XRCC3 xrcc3 product has the following accession number(s) (GI #153946427) (NCBI Accession #NP_001093588.1) (Uniprot Accession #O43542). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the XRCC3 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of HL60 cell lines, using XRCC3 antibody.)
Immunofluorescence (IF) (Immunofluorescence analysis of U2OS cell using XRCC3 antibody. Blue: DAPI for nuclear staining.)
This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified.
Immunogen Type: Recombinant Protein
Immunogen Description: Recombinant protein of human XRCC3. Target Name: XRCC3. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing XRCC3 are readily searchable from our website. Different antibodies against the same target such as XRCC3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. XRCC3 also interacts with the following gene(s): BRCA2, FANCG, RAD51B, RAD51C, RAD51D, RAD52, RECQL, XRCC2. Blood, Lymph Node tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Carcinoma, Carcinoma, Squamous Cell, Chromosome Aberrations, Genetic Predisposition to Disease, Head and Neck Neoplasms, Lung Neoplasms, Skin Neoplasms, Urinary Bladder Neoplasms are some of the diseases may be linked to XRCC3 Antibody. The following patways have been known to be associated with this gene.