|The YWHAZ ywhaz (Catalog #MBS280026) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Human 14-3-3 protein zeta/delta(YWHAZ) polyclonal antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s 14-3-3 protein zeta/delta can be used in a range of immunoassay formats including, but not limited to, Western Blot Analysis (WB), Immunohistochemistry (IHC), ELISA (EIA). Researchers should empirically determine the suitability of the YWHAZ ywhaz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The YWHAZ ywhaz product has the following accession number(s) (GI #21735625) (NCBI Accession #NP_663723.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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14-3-3 protein zeta/delta is a protein that in humans is encoded by the YWHAZ gene. This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Two transcript variants differing in the 5\' UTR, but encoding the same protein, have been identified for this gene.
Storage Buffer: PBS, pH: 7.20, 1% BSA, 0.02% Sodium azide.
Immunogen: Recombinant protein, corresponding to the N-term of human YWHAZ. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing YWHAZ are readily searchable from our website. Different antibodies against the same target such as YWHAZ may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adipose Tissue, Blood, Brain, Heart, Kidney, Liver, Lung, Muscle, Placenta, Prostate tissues are correlated with this protein. Adenocarcinoma, Breast Neoplasms, Carcinoma, Disease Models, Animal, Heart Diseases, Inflammation, Liver Diseases, Neoplasms, Experimental, Nervous System Diseases, Skin Diseases are some of the diseases may be linked to Rabbit anti-Human 14-3-3 protein zeta/delta(YWHAZ) polyclonal antibody. The following patways have been known to be associated with this gene.