|The ZAP-70 zap70 (Catalog #MBS8500846) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The ZAP-70 (Phospho-Tyr319) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ZAP-70 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA).
ELISA: 1:1000. Researchers should empirically determine the suitability of the ZAP-70 zap70 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ZAP-70 zap70 product has the following accession number(s) (GI #31455611) (NCBI Accession #NP_001070.2) (Uniprot Accession #P43403). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ZAP-70 (Phospho-Tyr319) Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts from Jurkat cells, using Zap-70 (Ab-319) antibody (Line1 and 2) and Zap-70 (Phospho-Tyr319) antibody (Line 3 and 4).)
Immunogen: The antiserum was produced against synthesized phosphopeptide derived from human Zap-70 around the phosphorylation site of tyrosine 319 (S-P-YP-S-D). All Sites: Human: Tyr319
Rat: Tyr314. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ZAP-70 are readily searchable from our website. Different antibodies against the same target such as ZAP-70 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone Marrow, Brain, Intestine, Kidney, Liver, Lymph Node, Mammary Gland, Spleen, Thymus tissues are correlated with this protein. Brain Diseases, Cell Transformation, Neoplastic, Congenital Abnormalities, Immunologic Deficiency Syndromes, Inflammation, Lymphoma, Necrosis, Neoplasms, Neoplasms, Experimental, Severe Combined Immunodeficiency are some of the diseases may be linked to ZAP-70 (Phospho-Tyr319) Antibody. ZAP-70 also interacts with the following gene(s): CBL, CD3E, CD5, FYN, GRB2, LAT, LCK, PTPN6, PTPRC, VAV1. The following patways have been known to be associated with this gene.