anti-ZIC3 antibody product blog
Tags: Antibody; Polyclonal Antibody; ZIC3; anti-ZIC3 antibody;
The ZIC3 zic3 (Catalog #MBS9208307) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZIC3 Antibody (N-term) reacts with Human (Predicted Reactivity: Mouse) and may cross-react with other species as described in the data sheet. MyBioSource\'s ZIC3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC).WB~~1:1000. Researchers should empirically determine the suitability of the ZIC3 zic3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ZIC3 zic3 product has the following accession number(s) (GI #4507973) (NCBI Accession #NP_003404.1) (Uniprot Accession #O60481). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ZIC3 Antibody (N-term) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of anti-ZIC3 Antibody (N-term) in HL60 cell line lysates (35ug/lane).ZIC3(arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ZIC3 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
ZIC3 is a member of the ZIC family of C2H2-type zinc finger proteins. This nuclear protein probably functions as a transcription factor in early stages of left-right body axis formation. Mutations in the gene encoding ZIC3 cause X-linked visceral heterotaxy, which includes congenital heart disease and left-right axis defects in organs.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ZIC3 are readily searchable from our website. Different antibodies against the same target such as ZIC3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Embryonic Tissue, Eye, Muscle tissues are correlated with this protein. ZIC3 also interacts with the following gene(s): CFC1, KLF4, NANOG, PBX1, SALL4, SMAD4, SOX2. The following patways have been known to be associated with this gene. Abnormalities, Multiple, Congenital Abnormalities, Craniofacial Abnormalities, Dextrocardia, Disease Models, Animal, Embryo Loss, Heart Defects, Congenital, Heterotaxy, visceral, X-linked, Neural Tube Defects, Respiratory Tract Diseases are some of the diseases may be linked to ZIC3 Antibody (N-term).