|The ZMIZ1 zmiz1 (Catalog #MBS151128) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZIMP10 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s ZIMP10 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF).
ZIMP10 antibody can be used for detection of ZIMP10 by Western blot at 0.5 mug/mL. Antibody can also be used for immunocytochemistry starting at 10 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the ZMIZ1 zmiz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ZMIZ1 zmiz1 product has the following accession number(s) (GI #31543543) (NCBI Accession #NP_65071) (Uniprot Accession #Q9ULJ6). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ZIMP10 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ZIMP10 in K562 cell lysate with ZIMP10 antibody at 0.5 μg/mL in (A) the absence and (B) the presence of blocking peptide)
Immunofluorescence (IF) (Immunofluorescence of ZIMP10 in K562 cells with ZIMP10 antibody at 20 μg/mL.)
Immunocytochemistry (ICC) (Immunocytochemistry of ZIMP10 in K562 cells with ZIMP10 antibody at 10 μg/mL.)
ZIMP10 Antibody: ZIMP10, also known as ZMIZ1, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein initially identified as a transcriptional co-activator of the androgen receptor (AR). ZIMP10 and the related protein ZIMP7 interact with PIAS3 and enhances AR-mediated transcription. Later experiments showed that ZIMP10 is also a co-activator of the p53 tumor suppressor. Mice deficient in ZIMP10 result in embryonic lethality by E10.5; these embryos reveal severe defects in the reorganization of the yolk sac vascular plexus, indicating that ZIMP10 plays an important role in proper vascular development.
Immunogen: ZIMP10 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ZIMP10.
Buffer: ZIMP10 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ZMIZ1 are readily searchable from our website. Different antibodies against the same target such as ZMIZ1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.