anti-ZNF536 antibody product blog
Tags: Antibody; Polyclonal Antibody; ZNF536; anti-ZNF536 antibody;
The ZNF536 znf536 (Catalog #MBS9413457) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF536 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ZNF536 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ZNF536 znf536 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The ZNF536 znf536 product has the following accession number(s) (GI #7662092) (NCBI Accession #NP_055532). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the ZNF536 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of ZNF536 in human brain tissue lysate with ZNF536 antibody at 1 ug/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of ZNF536 in human brain tissue with ZNF536 antibody at 5 ug/mL.)
ZNF536 is a recently identified zinc-finger protein that is expressed primarily in the developing nervous system and the cerebral cortex, hippocampus, and hypothalamus. ZNF536 possess ten zinc fingers and interacts with CtBP1, a corepressor for gene transcription. It is most closely related to transcriptional repressor ZNF219. Overexpression of ZNF536 in embryonic stem cells dramatically reduced the mRNA levels of neuronal marker genes such as Pax6, MAP2, and beta-tubulin III following retinoic acid (RA)-induced differentiation, while depletion of ZNF536 via RNAi resulted in elevated mRNA levels of these genes, indicating its role in inhibiting neuronal cell differentiation. Overexpression of RA receptor a rescues the inhibitory role of ZNF536, suggesting that ZNF536 might inhibit RA response element-mediated transcriptional activity.
Immunogen Type: Peptide
Immunogen Description: Raised against a 16 amino acid peptide from near the amino terminus of human ZNF536. Target Name: ZNF536. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ZNF536 are readily searchable from our website. Different antibodies against the same target such as ZNF536 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain tissues are correlated with this protein.