anti-ALK3 antibody product blogThe ALK3 bmpr1a (Catalog #MBS248900) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human ALK3 / BMPR1A reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s ALK3 / BMPR1A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB).
IHC-P (1:100), WB (1:1000). Researchers should empirically determine the suitability of the ALK3 bmpr1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ALK3 bmpr1a product has the following accession number(s) (GI #41349437) (NCBI Accession #NP_004320.2) (Uniprot Accession #P36894). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human ALK3 / BMPR1A with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-ALK3 / BMPR1A antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.)
Western Blot (WB) (Mouse Bmpr1a Antibody (Center) Western blot of SK-BR-3 cell line lysates (35 ug/lane). This demonstrates the Bmpr1a antibody detected the Bmpr1a protein (arrow).)
On ligand binding of BMP-2 and BMP-4, BMPR1A (a type I receptor) forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Targeted disruption of the BMPR1A receptor protein in the mesenchymal cells of the Mullerian ducts of mice leads to retention of oviducts and uteri in males.
Target Species: Human
Immunogen Description: KLH-conjugated synthetic peptide from internal region of human Mouse Bmpr1a. Immunogen Type: Synthetic peptide
Immunogen: ALK3 / BMPR1A antibody was raised against kLH-conjugated synthetic peptide from internal region of human Mouse Bmpr1a.
Antigen Modification: aa169-197. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ALK3 are readily searchable from our website. Different antibodies against the same target such as ALK3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.