anti-ASB2 antibody product blogThe ASB2 asb2 (Catalog #MBS613477) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Ankyrin repeat and SOCS box-containing protein (Asb-2) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Ankyrin repeat and SOCS box-containing protein can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Western blot analysis of Asb-2 using antibody at 1:1,000 dilution against 15 ug/lane of human spleen lysate (lane 1) and lung lysate (lane 2).
Dilution: Western blot: 1:500-1,000. Researchers should empirically determine the suitability of the ASB2 asb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The ASB2 asb2 product has the following accession number(s) (GI #289666524) (NCBI Accession #BAI77868.1) (Uniprot Accession #Q96Q27). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
The ankyrin repeat and SOCS box-containing (Asb) protein family is comprised of members which each contain "SOCS boxes" but differ from other families of protein in the motifs they contain upstream of the SOCS box(1). SOCS boxes are carboxy-terminal regions of homology found in the suppressor of cytokine signaling family of proteins. The box region is thought to be the point of interaction between SOCS proteins and E3 ubiquitin ligases. Asb-2 has been found to induce growth inhibition and chromatin condensation in myeloid leukemia cells(2).
Immunogen: Synthetic peptides containing amino acids 75-93 and 348-368 of human Asb-2 protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ASB2 are readily searchable from our website. Different antibodies against the same target such as ASB2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Necrosis, Neoplasms are some of the diseases may be linked to Ankyrin repeat and SOCS box-containing protein (Asb-2). Blood, Brain, Heart, Liver, Muscle, Stomach tissues are correlated with this protein. ASB2 also interacts with the following gene(s): ASB17, CUL2, CUL5, FLNB, RNF7, UBC.