anti-BCOR antibody product blogThe BCOR bcor (Catalog #MBS9214388) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCOR Antibody (Center S1122) reacts with Human, mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s BCOR can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS).
WB~~1:1000. Researchers should empirically determine the suitability of the BCOR bcor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The BCOR bcor product has the following accession number(s) (GI #183396783) (NCBI Accession #NP_001116855.1) (Uniprot Accession #Q6W2J9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the BCOR Antibody (Center S1122) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of BCOR Antibody (Center S1122) in 293 cell line lysates (35ug/lane). BCOR (arrow) was detected using the purified Pab.)
Western Blot (WB) (Western blot analysis of BCOR Antibody (Center S1122) in mouse stomach tissue lysates (35ug/lane). BCOR (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC) (BCOR Antibody (Center S1122) IHC analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCOR Antibody (Center S1122) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS) (BCOR Antibody (Center S1122) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
BCOR was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs.
Antigen Type: Synthetic Peptide. Antigen Source: HUMAN. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing BCOR are readily searchable from our website. Different antibodies against the same target such as BCOR may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.