anti-Clock antibody product blogThe Clock clock (Catalog #MBS618324) is an Antibody produced from Host: Rabbit
Source: Human and is intended for research purposes only. The product is available for immediate purchase. The Anti - Clock reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Clock can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot.
Western blot: 1-10ug/ml using ECL. Immunohistochemistry: not tested. It is recommended that the antibody be tried at 2-20ug/ml. ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide per well. Researchers should empirically determine the suitability of the Clock clock for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Clock clock product has the following accession number(s) (GI #2275619) (Uniprot Accession #O15516). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
CLOCK, a basic helix-loop-helix (bHLH)/PAS protein, is an important factor in the molecular clock mechanism. Mutations in this protein lead to abnormal circadian behavior and defective transcriptional activity. CLOCK has been shown to interact strongly with other bHLH-PAS proteins such as MOP3, a BMAL1 isoform.
Immunogen: A 20 amino acid peptide near the C-terminus of human Clock (1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Clock are readily searchable from our website. Different antibodies against the same target such as Clock may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Muscle, Skin, Vascular tissues are correlated with this protein. Clock also interacts with the following gene(s): ARNTL, ARNTL2, PER3. The following patways have been known to be associated with this gene. Body Weight Changes, Central Nervous System Diseases, Cognition Disorders, Inflammation, Intestinal Diseases, Liver Diseases, Mental Disorders, Neoplasms, Neurologic Manifestations, Obesity are some of the diseases may be linked to Anti - Clock.