anti-FOXO4 antibody product blogThe FOXO4 foxo4 (Catalog #MBS629222) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The AFX, phosphorylated (Ser197) (Forkhead Box Protein O4, Fork Head Domain Transcription Factor AFX1, FOXO4, AFX1, MLLT7) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s AFX can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Western Blot:1:500-1:1,000
Immunohistochemistry:1:50-1:100. Researchers should empirically determine the suitability of the FOXO4 foxo4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The FOXO4 foxo4 product has the following accession number(s) (GI #1418759) (Uniprot Accession #P98177). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
AFX, phosphorylated (Ser197) (Forkhead Box Protein O4, Fork Head Domain Transcription Factor AFX1, FOXO4, AFX1, MLLT7)
Several studies indicate that FKHR and AFX, mammalian homologues of the Caenorhabditis elegans forkhead transcription factor DAF-16, function in the insulin signaling pathway promoter contains one IRS, while in the IGFBP-1 promoter two copies of IRS are arranged as an inverted palindrome. Three tandem copies of IRSs are present in the G6Pase. AFX has been recently shown to serve as a substrate of PKB both in vitro and in vivo, and its transcriptional activity is inhibited by phosphorylation.
Immunogen: AFX, phosphorylated (Ser197). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing FOXO4 are readily searchable from our website. Different antibodies against the same target such as FOXO4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Embryonic Tissue, Eye, Intestine, Kidney, Liver, Ovary, Prostate tissues are correlated with this protein. FOXO4 also interacts with the following gene(s): AKT1, AKT2, CCND1, CREBBP, CTNNB1, FOXG1, SMAD4. Breast Neoplasms, Cardiovascular Diseases, Colonic Neoplasms, Colorectal Neoplasms, Diabetes Mellitus, Inflammation, Ischemia, Lung Neoplasms, Metabolic Diseases, Neoplasms are some of the diseases may be linked to AFX, phosphorylated (Ser197) (Forkhead Box Protein O4, Fork Head Domain Transcription Factor AFX1, FOXO4, AFX1, MLLT7).