anti-IL21 antibody product blogThe IL21 il21 (Catalog #MBS630074) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Interleukin 21, IN (IL-21 IN) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Interleukin 21, IN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Suitable for use in Western Blotting.
Dilution: Western Blot: 0.5-1ug/ml. Researchers should empirically determine the suitability of the IL21 il21 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The IL21 il21 product has the following accession number(s) (GI #11093536) (Uniprot Accession #Q9HBE4). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Immunogen: Synthetic peptide (TCPSCDSYEKKPPKE) corresponding to amino acids 121 to 135 of human IL-21 precursor (1). Positive Control: Human HL-60 and THP-1 cell lysates. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing IL21 are readily searchable from our website. Different antibodies against the same target such as IL21 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Celiac Disease, Dermatitis, Atopic, Inflammation, Leukopenia, Lupus Erythematosus, Systemic, Lymphoma, Mammary Neoplasms, Experimental, Neoplasms, Thrombocytopenia, Thyroid Diseases are some of the diseases may be linked to Interleukin 21, IN (IL-21 IN). IL21 also interacts with the following gene(s): IL21R.