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anti-p53 antibody product blog

Tags: Antibody; anti-p53 antibody; p53; Polyclonal Antibody;

     The p53 tp53 (Catalog #MBS856937) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The p53 (Ab-15) Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s p53 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
WB: 1:500~1000
IHC: 1:50~1:100. Researchers should empirically determine the suitability of the p53 tp53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The p53 tp53 product has the following accession number(s) (GI #120407068) (NCBI Accession #NP_000537.3) (Uniprot Accession #P04637). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the p53 (Ab-15) Antibody with the following immunoassay(s):
Immunohistochemistry (Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p53 (Ab-15) antibody.)
Immunohistochemistry p53.

Western Blot (Western blot analysis of the extracts from HeLa cells untreated or treated with hydroxyurea using p53 (Ab-15) antibody (Line1 and 2) and p53 (phospho-Ser15) antibody (Line3 and 4).)
Western Blot p53.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing p53 are readily searchable from our website. Different antibodies against the same target such as p53 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Breast Neoplasms, Carcinoma, Carcinoma, Small Cell, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Colorectal Neoplasms, Glioma, Neoplasm Metastasis, Sarcoma, Urogenital Neoplasms are some of the diseases may be linked to p53 (Ab-15) Antibody. Blood, Brain, Kidney, Liver, Lung, Lymph, Muscle, Prostate, Skin, Vascular tissues are correlated with this protein. p53 also interacts with the following gene(s): ATM, BAX, BCL2L1, BCR, BRCA1, BRCA2, CDKN1A, CHEK2, MDM2, PTGS2.
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