anti-TERT antibody product blogThe TERT tert (Catalog #MBS624540) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TERT, phosphorylated (Tyr707) (Telomerase Reverse Transcriptase, Telomerase Catalytic Subunit, HEST2, Telomerase-associated Protein 2, TP2, EST2, TCS1, TRT) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TERT can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Gel Shift Assay (GS/EMSA).
Suitable for use in ELISA and Dot Blot.
Dilution: ELISA: 1:1,000
Dot Blot: 1:500. Researchers should empirically determine the suitability of the TERT tert for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TERT tert product has the following accession number(s) (GI #301129200) (NCBI Accession #NP_001180305.1) (Uniprot Accession #O14746). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
TERT, phosphorylated (Tyr707) (Telomerase Reverse Transcriptase, Telomerase Catalytic Subunit, HEST2, Telomerase-associated Protein 2, TP2, EST2, TCS1, TRT)
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks.
Immunogen: Synthetic phosphopeptide corresponding to amino acid residues surrounding Tyr707 of human TERT (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TERT are readily searchable from our website. Different antibodies against the same target such as TERT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Cell Transformation, Neoplastic, Heart Diseases, Inflammation, Liver Neoplasms, Lung Diseases, Lung Neoplasms, Necrosis, Neoplasms, Neoplasms, Experimental, Reperfusion Injury are some of the diseases may be linked to TERT, phosphorylated (Tyr707) (Telomerase Reverse Transcriptase, Telomerase Catalytic Subunit, HEST2, Telomerase-associated Protein 2, TP2, EST2, TCS1, TRT). TERT also interacts with the following gene(s): AKT1, DKC1, SMARCA4, SMG6, SP1, TEP1.