anti-TNNI3 antibody product blogThe TNNI3 tnni3 (Catalog #MBS535361) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Troponin I antibody (Cardiac) reacts with Specific for Human cardiac Troponin I (88-106) and may cross-react with other species as described in the data sheet. MyBioSource\'s Troponin I can be used in a range of immunoassay formats including, but not limited to, User optimized. Researchers should empirically determine the suitability of the TNNI3 tnni3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TNNI3 tnni3 product has the following accession number(s) (GI #50978684) (NCBI Accession #NP_001003041.1) (Uniprot Accession #Q8MKD5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Goat polyclonal Troponin I antibody (Cardiac).
Biological Significance: Troponin I is a part of the troponin complex. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: Troponin I antibody (cardiac) was raised in goat using human cardiac troponin I as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TNNI3 are readily searchable from our website. Different antibodies against the same target such as TNNI3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Heart, Muscle tissues are correlated with this protein. CARDIOMYOPATHY, FAMILIAL HYPERTROPHIC, 7, Cardiomyopathies, Cardiomyopathy, Dilated, Cardiomyopathy, Familial Restrictive, 1, Cardiomyopathy, Hypertrophic, Familial, Cardiomyopathy, Restrictive, Fibrosis, Heart Diseases, Hypertension, Nervous System Diseases are some of the diseases may be linked to Troponin I antibody (Cardiac). TNNI3 also interacts with the following gene(s): MYL3, TNNC1, TNNT1, TNNT2, TNNT3, TPM1, TPM3. The following patways have been known to be associated with this gene.