anti-YWHAB antibody product blogThe YWHAB ywhab (Catalog #MBS9416465) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The 14-3-3 protein beta/alpha Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s 14-3-3 protein beta/alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Western Blot: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200. Researchers should empirically determine the suitability of the YWHAB ywhab for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The YWHAB ywhab product has the following accession number(s) (GI #4507949) (NCBI Accession #NP_003395.1) (Uniprot Accession #P31946). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the 14-3-3 protein beta/alpha Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (All lanes: 14-3-3 protein beta/alpha antibody at 2ug/ml)
Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embeded human kidney using at dilution of 1:50.)
Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases.Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.
Immunogen: Recombinant Human 14-3-3 protein beta/alpha protein. Immunogen Type: Protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing YWHAB are readily searchable from our website. Different antibodies against the same target such as YWHAB may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Brain, Ganglia, Kidney, Liver, Lung, Muscle, Nerve, Prostate, Vascular tissues are correlated with this protein. Carcinoma, Carcinoma, Hepatocellular, Cardiovascular Diseases, Inflammation, Liver Diseases, Liver Neoplasms, Neoplasm Metastasis, Nervous System Diseases, Neurodegenerative Diseases, Seizures are some of the diseases may be linked to 14-3-3 protein beta/alpha Polyclonal Antibody.